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Riley Children's Health

Fertility Preservation Program

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The Riley Children's Fertility Preservation Program aims to provide patients with the highest quality of life during and after treatment. Our program provides education and counseling for children at risk for long-term fertility or reproductive health issues. Our program also offers fertility preservation options when possible.

Fertility Services and Treatments

Fertility Services and Treatments

Survival rates among pediatric and adolescent cancer patients continue to increase due to the development of more effective cancer treatments. As a result, many childhood cancer survivors are reaching their reproductive years and wish to start their own families. However, certain cancer treatments may impact your child's ability to have children in the future.

Before their cancer treatment starts, it is important to have a conversation with your child's doctor about any fertility questions.

We understand that planning for your child's future after a cancer diagnosis is complex and may feel awkward.

Our program works closely with patients and caregivers to help inform you of the information to make the best decision for your child's future.

Our team takes a comprehensive approach to providing infertility risk counseling, fertility preservation options and reproductive/sexual health in patients receiving treatment that is harmful to the reproductive organs.

Our team of highly-skilled providers addresses the complex health care and quality-of-life concerns our young cancer patients face, whose fertility may be threatened by their specific cancer or its treatment.

Cancer treatments that can affect a child's fertility include:

  • Surgery, which may include the removal of one or both sexual reproductive organs (testicles or ovaries)
  • Radiation therapy
  • Chemotherapy

Side effects of cancer treatments that may affect fertility include:

  • Changes to sperm production in boys, most often a decrease in sperm produced by the testes
  • Lowered number of eggs in girls
  • Changes in hormone production, such as a decrease in estrogen or testosterone
  • Harm to healthy cells in the reproductive organs

Your child's primary oncologist will consult with our team when diagnosed with cancer. One of our specialists will determine if there is a low, medium or high risk of cancer treatment affecting your child's long-term fertility. Then, we will discuss options together and help you determine the best plan.

Fertility Preservation Options

Fertility preservation options for patients with male reproductive organs include:

  • Semen cryopreservation (freezing the semen)
  • Referrals for removing reproductive organs or tissues to preserve them
  • Testicular tissue cryopreservation (freezing testicular tissue)

Fertility preservation options for patients with female reproductive organs include:

  • Use of medication to suppress periods (menstruation) that may help preserve eggs
  • Oocyte cryopreservation (freezing the egg before fertilization)
  • Embryo cryopreservation (freezing a fertilized egg)
  • Ovarian tissue cryopreservation (freezing the tissue of the ovaries)
  • Referrals for preserving reproductive organs or tissues

Our specialists have extensive clinical experience working in fertility preservation. Our team includes:

  • Pediatric oncologists
  • Pediatric urologists
  • Adolescent gynecologists
  • Reproductive endocrinologists
  • Nurse practitioners
  • Physician assistants
  • Genetic counselors
  • Nurse Navigators

Conditions & Services

Conditions Treated

Our pediatric specialists provide patient- and family-centered care for most related conditions. The links below provide more specific information about some, but not all, of the conditions that we treat.

  • Childhood Brain & Spinal Cord Tumors
  • Germ Cell Tumors
  • Head & Neck Masses
  • Langerhans Cell Histiocytosis
  • Leukemia
  • Liver Tumors
  • Lymphoma
  • Neuroblastoma
  • Osteosarcoma
  • Ovarian Cysts & Tumors
  • Pediatric Ewing Sarcoma
  • Retinoblastoma
  • Rhabdomyosarcoma
  • Sacrococcygeal Teratoma

Services Offered

We offer a number of different Fertility Preservation Program services. Below are some, but not all, of the services that we provide. If you have a question about a specific service that is not listed here, please contact our program.

  • Adolescent Consultation
  • Spiritual & Psychosocial Support
  • Virtual Visits

Doctors and Locations

Doctors

Locations

Locations

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Patient & Family Resources

Patient & Family Resources

Below is a list of services provided by Riley Children's to help support your child and family through their cancer care with us. These are just a few of the support services provided.

Learn more about our Patient and Family Support Services.

Resources

  • School Program

    With our school program, your child does not have to miss out on important education while receiving treatment.

Related Programs & Departments

Related Programs & Departments

We provide multispecialty care for a number of conditions. Below are links to our related programs & departments.

  • Adolescent Medicine
  • Pediatric Cancer & Blood Disorders
  • Children's Clinical Research Center
  • Comprehensive Hematology Program
  • Disorders of Sex Development
  • Gender Health Program
  • Herman B Wells Center for Pediatric Research
  • Leukemia & Lymphoma Program
  • Sarcoma & Solid Tumor Program
  • Sickle Cell Program

Health Professionals

For Health Professionals

Refer A Patient

Refer A Patient

To refer a patient to the Fertility Preservation Program, please call 317.944.2143.

Refer A Patient

Research

Ranked in the top 25 by U.S. News & World Report, Riley’s Center for Cancer & Blood Diseases is affiliated with the IU Health Melvin and Bren Simon Cancer Center, the state’s only National Cancer Institute-designated cancer center for clinical care.

Riley Children’s is a member of the Children’s Oncology Group Phase I Consortium. Patients can access the latest clinical trials and leading-edge medications, all while under the care of highly skilled providers.

Find a Clinical Trial

Education

The Fertility Preservation Program at Riley Children's helps train the next generation of pediatric hematologists and oncologists. Pediatric oncology/hematology fellows at the Indiana University School of Medicine learn about the latest advancements in personalized cancer treatment by spending part of their training with our team.

Education Resources:
  • Fellowship
Riley Children's Health Indiana University School of Medicine
Designated as Best Children's Hospitals by U.S. News & World Report, Ranked in 10 Specialties in 2023-24

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Indiana University Health
Find adult services at iuhealth.org

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Designated as Best Children's Hospitals by U.S. News & World Report, Ranked in 10 Specialties in 2023-24

©2025 Riley Hospital for Children at
Indiana University Health
Find adult services at iuhealth.org


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