Eosinophilic disorders are characterized by increased levels of eosinophils in one or more places in the digestive tract. Eosinophils are white blood cells that play a role in fighting parasites and allergic reactions. The esophagus, stomach, small intestine and large intestine (colon) may be affected.
There are three types of eosinophilic disorders:
Eosinophilic esophagitis (EoE) is the most common eosinophilic disorder. EoE is characterized by elevated eosinophils in the esophagus. EoE is believed to be an allergic reaction most likely to food. There is some evidence to suggest that the allergic substance may be present in the environment. Many patients with EoE also suffer from other allergic diseases, including asthma, eczema and sinus disease.
The symptoms of eosinophilic esophagitis vary and include:
These symptoms may be misdiagnosed as gastroesophageal reflux disease (GERD).
Eosinophilic gastroenteritis (EGE) is a rare condition that damages the stomach. Eosinophils accumulate in the stomach and cause inflammation.
The symptoms of eosinophilic gastroenteritis (EGE) include:
Eosinophilic colitis (EC) occurs when eosinophils build up in the colon. They can cause injury and inflammation to different layers of colon tissues.
The symptoms of eosinophilic colitis (EC) include:
A pediatric gastroenterologist can perform the following exams and tests to help make a diagnosis:
Treatments for eosinophilic disorders include a range of options, such as:
Visit the websites below to find support groups and services and learn more about eosinophilic disorders.
Riley at IU Health offers a broad range of supportive services to make life better for families who choose us for their children's care.
This website from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition provides education and information about eosinophilic disorders and eosinophilic esophagitis.
This website offers resources for patients and families living with eosinophilic asthma.
This website provides an overview of eosinophilic esophagitis and other allergy-related information.
This website offers resources to improve the lives of patients and families living with eosinophilic disorders.
This website delivers extensive information about food allergies for patients and families coping with related conditions, including eosinophilic esophagitis.
The Eosinophilic Disease Program at Riley at IU Health provides family-centered clinical care and education to children and families living with food allergies and eosinophilic gastrointestinal disorders (EGIDs).
Our pediatric specialists take a strong interest in advancing the understanding of esophageal diseases, including eosinophilic esophagitis (EoE). You and your child may be offered participation in research studies. These studies may help improve the care of children with similar problems. We encourage you to ask plenty of questions in order to make an informed decision.
In addition to our primary hospital location at the Academic Health Center in Indianapolis, IN, we have convenient locations to better serve our communities throughout the state.
Sort through 7 facilities offering Eosinophilic Disorders care by entering your city or zip below.