Ranked in the top 25 by U.S. News & World Report, Riley Children’s Health pediatric oncology combines leading-edge medicine with holistic, personalized care. Partnering with our skilled experts means your patients will have access to the latest clinical trials and therapeutic options to treat the full spectrum of pediatric cancers, including aggressive disease and cancers that are no longer responsive to conventional therapy.
Riley at IU Health treats more than 80% of children with cancer in Indiana with an 84% five-year cancer survival rate.
Refer a patient to Riley Hematology/Oncology
For a seamless referral process, we offer direct access to our outpatient referral coordinator to ensure your patients are efficiently scheduled with the Riley physician who best fits their needs.
There are three easy ways to refer a patient to our program:
- Contact our outpatient referral coordinator directly at 317.944.2143.
- Email the coordinator at PedsHemOncReferral@iuhealth.org.
- Go to rileychildrens.org/refer. Select Cancer and Blood Diseases from the drop-down menu. Download and fax the completed form to 317.944.3107.
Riley’s nationally recognized pediatric oncology program offers patients and families:
Riley’s nationally recognized pediatric oncology program offers patients and families:
Unmatched clinical expertise
- Only facility in Indiana offering pediatric stem cell transplant, CAR T-cell therapy and immune effector cell therapy for pediatric patients
- Indiana’s only pediatric cancer program to offer precision genomics—individualized treatment for children with relapsed or aggressive cancer
- Affiliated with Indiana’s only NCI-designated Comprehensive Cancer Center—Indiana University Simon Cancer Center
- Antibody therapy for neuroblastoma
- Dedicated pediatric neuroradiology team
- Greater access to the latest clinical trials and therapeutic options to treat the full spectrum of pediatric cancers, including aggressive disease and cancers that are no longer responsive to conventional therapy
- Access to clinical trials through CureWorks, Children's Oncology Phase 1 Consortium and the Pediatric Neuro-Oncology Consortium
- Open clinical trials in oncology: 72
- Open clinical trials in hematology: 5
- View full list of open clinical trials for 2023
Multidisciplinary, holistic care
- Collaboration with other medical specialists at Riley to help ensure the best possible patient outcomes
- Indiana’s largest and most skilled rehabilitation team
- Long-term survivorship program features holistic care for pediatric cancer survivors, including multidisciplinary teams, exercise programs and more
- Adolescent and Young Adult program is the only program in the state of Indiana to specifically focus on bridging the gap between pediatric and adult oncology for a unique population of patients ranging in age from 15-39
Additional patient- and family-centered support services
- Full floor of the hospital dedicated to pediatric cancer care
- Educational support for school-aged children through the Riley School Program
- Comprehensive inpatient child life program; art and music therapy, pet therapy and a family library
- Ronald McDonald House, a supportive “home-away-from-home” for families whose children are receiving care at Riley
Learn more about Riley Family Support Services.
Specialized pediatric cancer treatment programs
Specialized pediatric cancer treatment programs
Our physicians see more than 300 new oncology patients and over 800 new hematology patients each year. Riley pediatric cancer teams manage more than 13,000 outpatient visits annually, including a comprehensive telehealth program offering virtual visits.
Stem Cell Transplant and Cellular Therapy Program
We use autologous and allogeneic transplants and CAR-T cell therapy to fight acute lymphoblastic leukemia, acute myeloid leukemia, sickle cell disease, immunodeficiency, bone marrow failure and other non-malignant conditions. Learn more about our Stem Cell Transplant Program.
Allogeneic transplant 100-day survival rate in 2020: 100%
Leukemia and Lymphoma Program
The largest leukemia and lymphoma program of its kind in Indiana, Riley offers the latest and most innovative treatments, including CAR-T cell therapy, for newly diagnosed and relapsed childhood leukemia and lymphomas. Our highly trained physicians have diagnosed and treated more than 1,000 children in the past decade, with very high cure rates.
Solid Tumor Program
Our oncologists have extensive experience in diagnosing and treating all types of solid tumor malignancies. Riley patients have access to the latest therapies, including the leading-edge antibody therapy for neuroblastoma known as Hu3F8.
Riley at IU Health is the only hospital in Indiana offering Hu3F8, a novel treatment for solid tumors, and has treated patients from around the world.
Neuro-Oncology Program
Riley’s multidisciplinary retinoblastoma program is one of the only comprehensive programs of its kind in the Midwest. Focused on delivering comprehensive clinical care from diagnosis to long-term follow-up, our Neuro-Oncology Program provides supportive care to maximize quality of life for children and their caregivers. Collaborations with essential specialists help ensure complete care for patients with brain and spinal cord tumors.
Comprehensive Hematologic Programs
Riley hematologists annually treat nearly 3,000 children and adolescents with blood disorders.
Hemostasis and Thrombosis Program
We provide multidisciplinary care to pediatric patients with bleeding and clotting disorders, including heavy menstrual bleeding and vascular anomalies. Our team also partners with the Herzog Laboratory at IU School of Medicine, a leader in research for alternative forms of treatment for children with hemophilia.
Hemoglobinopathy Program
Riley has the largest pediatric sickle cell program in the state and the only stem cell transplant center for non-malignant transplants. Our program serves children with sickle cell disease and other hemoglobinopathies such as thalassemia.
Bone Marrow Failure Program
Our program includes an internationally known, NCI-funded research laboratory employing functional genomics and super-resolution imaging to understand the mechanistic origins of genomic instability in Fanconi anemia and other bone marrow failure/cancer predisposition syndromes.
Delivering a higher level of pediatric cancer care
Exclusive CureWorks Partnership Expands Clinical Trial Options
A unique collaboration among five elite academic children’s hospitals that includes Riley at IU Health:
- Enables our oncologists to offer more clinical trial options in CAR T-cell therapy science to children with cancer.
- Supports member hospitals in launching and participating in exclusive clinical trials.
- Streamlines immunotherapy production, clinical trial enrollment and the trial coordination process.
- Expands access to the latest treatments, allowing Riley patients to get more advanced care closer to home.
Learn more about Riley’s membership in CureWorks.
Precision Genomics Program Customizes Therapies for Aggressive Disease
More than 290 pediatric patients have been evaluated through our Precision Genomics Program, and nearly a quarter of those patients are receiving recommended therapy.
- An innovative approach uses genetic testing to identify DNA, RNA and proteins in cancer cells that can be precisely targeted with different treatments.
- After testing is interpreted, we research therapeutic options and facilitate tumor board in collaboration with the treating physician.