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Riley Children's Health

Vascular Anomalies Program

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The Vascular Anomalies Program at Riley Children’s Health provides high-quality, expert medical care for children experiencing any type of vascular anomaly.

About Our Program

The vascular anomalies program at Riley Children’s Health sees patients of all ages–from children to adults–with any type of vascular anomaly. Our multidisciplinary team, including specialists trained in hematology, dermatology, plastic surgery, otolaryngology, interventional radiology, physical therapy, and more, offers a comprehensive range of treatment options to reach each individual’s needs. Through each stage of our program, patients are in caring, expert hands from diagnosis to treatment, recovery, and beyond.

Vascular Anomalies

Vascular anomalies are conditions affecting the veins, arteries, capillaries, lymphatic vessels, or a combination of these, often present at birth or later in life. They range from simple birthmarks to complex issues that can cause severe symptoms like pain, bleeding, disfigurement, or problems with swallowing or breathing. Vascular anomalies can be life-threatening. There are many subtypes of vascular anomalies and many treatment options that include medications, procedures, and surgeries.

Types of Vascular Anomalies

Vascular anomalies can be divided into two main types:

  1. Vascular tumors are rare and non-cancerous conditions that include infantile hemangioma, congenital hemangioma, Kaposiform hemangioendothelioma, pyogenic granuloma, and others.
  2. Vascular malformations are abnormalities of blood or lymphatic vessels that form during development and tend to grow with the patient. Vascular malformations can involve capillaries, arteries, veins, lymphatic vessels, or a combination of these, and they can be associated with complex syndromes that may involve other problems.

Conditions We Treat

Conditions We Treat

Our pediatric specialists provide patient- and family-centered care for all types of vascular anomalies. The list below includes many, but not all, of the conditions that we treat. Please contact the team if you have a question about a condition not listed, as we likely are able to treat it.

Vascular Tumors

  • Hemangiomas
    • Infantile hemangioma
    • Congenital hemangioma
    • Hemangioma associated with syndromes such as PHACE or LUMBAR syndrome
    • Other hemangiomas, such as spindle-cell or epithelioid hemangioma
  • Kaposiform hemangioendothelioma/tufted angioma
  • Pyogenic granuloma
  • Other rare vascular tumors
    • Non-cancerous vascular tumors
    • Very rare malignant (cancerous) vascular tumors such as angiosarcoma

Vascular Malformations

  • Capillary malformations (also known as port-wine stain, port-wine birthmark, or pigmented birthmark)
    • Capillary malformation-arteriovenous malformation syndrome (CM-AVM)
    • Sturge-Weber syndrome
    • Hereditary Hemorrhagic Telangiectasia is cared for by Riley specialists outside of the Vascular Anomalies program
  • Venous malformations
    • Blue rubber bleb nevus syndrome
    • Glomuvenous malformation
  • Arteriovenous malformations (AVM)
    • Capillary malformation-arteriovenous malformation syndrome (CM-AVM)
  • Cystic lymphatic malformations
  • Complex lymphatic malformations
    • Generalized lymphatic anomaly (GLA)
    • Kaposiform lymphangiomatosis (KLA)
    • Gorham-Stout disease (GSD)
    • Central conducting lymphatic anomaly (CCLA)
  • Combined vascular malformations
    • Capillary-venous malformation
    • Lymphatic-venous or venolymphatic malformation
    • Capillary-lymphatic-venous malformation (including Klippel-Trenaunay syndrome and CLOVES syndrome)

Syndromes Associated with Vascular Malformations

  • PIK3CA-related overgrowth spectrum (PROS) conditions which include (among many others):
    • Klippel-Trenaunay syndrome
    • Microcephaly-capillary malformation (MCAP or M-CM)
    • CLOVES syndrome
    • Fibroadipose infiltrating lipomatosis/facial infiltrating lipomatosis
    • CLAPO syndrome
  • Parkes Weber syndrome
  • Sturge-Weber syndrome
  • PHACE syndrome
  • LUMBAR syndrome (also known as SACRAL or PELVIS syndrome)
  • Proteus syndrome
  • Blue rubber bleb nevus syndrome
  • Maffucci syndrome
  • PTEN hamartoma tumor syndrome (PHTS)
    • Cowden syndrome
    • Bannayan-Riley-Ruvalcaba syndrome

Conditions & Services

Services Offered

Our pediatric vascular specialists create a custom treatment plan for each patient based on their particular need. Below are some, but not all, of the services that we provide to treat vascular anomalies. If you have a question about a specific service that is not listed here, please contact our program.

  • Embolization
  • Laser Skin Therapy
  • Sclerotherapy

Providers and Locations

Providers

Our multidisciplinary, board-certified specialists often collaborate with institutions–the Consortium of iNvestigators of Vascular Anomalies (CaNVAS) and the International Society for the Study of Vascular Anomalies (ISSVA)–to advance care for these rare conditions.

Learn more about the medical team that makes up the Vascular Anomalies Program:

Locations

Locations

In addition to our primary hospital location at the Academic Health Center in Indianapolis, IN, we have convenient locations to better serve our communities throughout the state.

Sort through 4 facilities offering Vascular Anomalies Program care by entering your city or zip below.

See all facilities →

Program Forms & Resources

Program Forms & Resources

Riley Children's Health provides the following forms for parents, healthcare providers and personnel. We have also curated relevant resources from other websites and provided links with brief descriptions of the information that is available.

Resources

  • Hemangioma Investigator Group

    The Hemangioma Investigator Group provides this educational website for parents of children with infantile hemangiomas.

  • PHACE Syndrome Community

    This is a parent organization for patients with a complicated infantile hemangioma associated with PHACE syndrome.

  • Foundation for Faces of Children

    This nonprofit organization provides educational resources and support to families of children born with vascular anomalies and other craniofacial conditions.

  • Little Baby Face Foundation

    This foundation helps families with children who have facial anomalies and provides information on its website about vascular anomalies.

Related Programs & Departments

Related Programs & Departments

We provide multispecialty care for a number of conditions. Below are links to our related programs & departments.

  • Comprehensive Hematology Program
  • Dermatology
  • Ear, Nose & Throat
  • Interventional Radiology Program
  • Pediatric Ophthalmology
  • Pediatric Orthopedics & Sports Medicine
  • Physical Therapy & Occupational Therapy
  • Plastic Surgery

Health Professionals

For Health Professionals

The Vascular Anomalies Program at Riley Children’s Health works with referring physicians in Indiana and beyond to provide advanced diagnosis and treatment for patients with vascular malformations and hemangiomas.

Refer A Patient

Refer A Patient

We have specialists in all areas of vascular anomalies to which children and adults can be referred. To refer, submit a referral form online, call 317.944.5576, fax 317.944,3107 or email PedsHemOncReferral@iuhealth.org. For inquiries prior to referral, please call 1.844.MYRILEY (1.844.697.4539). For referrals specific to hemangioma, contact the Hemangioma Clinic through the Department of Dermatology at 317.944.7744.

Before you refer to the vascular anomalies team, please ensure you provide your patient with the following items so we can provide the best care possible:

  • Recent clinical notes
  • Results of laboratory studies such as blood counts and blood clotting labs
  • Reports and images from any radiology studies. Please contact our team for details.
  • A list of all procedures related to the vascular anomaly including dates, type of procedure, and location of procedure
  • Any reports generated from that procedure (such as endoscopy reports, operative reports, pathology reports)
  • Reports from any genetic testing related to the vascular anomaly
  • Medication history
  • Growth curves (height, weight, head circumference) for patients younger than 18 years old

Education

In partnership with the Indiana University School of Medicine, Riley Children’s provides a wide variety of excellent training opportunities for medical students, residents, and fellows. The Vascular Anomalies Program offers observational opportunities for residents and fellows.

Education Resources:
  • Medical Students
  • Residents & Fellows
Riley Children's Health Indiana University School of Medicine
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Designated as Best Children's Hospitals by U.S. News & World Report, Ranked in 10 Specialties in 2023-24

©2025 Riley Hospital for Children at
Indiana University Health
Find adult services at iuhealth.org


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