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Lymphadenopathy

Lymphadenopathy
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The lymphatic system is part of the body’s immune system that fights disease and infections. Lymph nodes are tiny, bean-shaped organs that help destroy infectious germs such as viruses and bacteria.

Swelling of the lymph nodes is a condition called lymphadenopathy. Swollen lymph nodes can be a normal occurrence and may not show an underlying disorder or condition or require treatment.

Lymphadenopathy occurs when lymph nodes in a specific area of the body (such as the head, neck, armpits, groin, abdomen or chest area) or throughout the whole body become enlarged. In children, swollen lymph nodes often appear as small, movable lumps under the skin. If a lymph node becomes very swollen, it may indicate an underlying illness.

Lymphadenopathy is a common response to illnesses such as an upper respiratory infection or strep throat.

Symptoms of lymphadenopathy may include:

  • Swollen, enlarged lumps in the neck, back of the head, armpits, groin or chest area
  • Fever
  • A lymph node that is tender, feels hard or is draining pus
  • Unexplained weight loss
  • Recent illness

For a lymph node that is very painful or draining pus, see a doctor immediately.

Diagnosis of Lymphadenopathy

If your child has swollen lymph nodes, the doctor will do a physical examination and ask about:

  • Symptoms and medical history
  • Location of swollen nodes
  • How long nodes have been swollen
  • Pain
  • Recent injuries or infections

Your child’s doctor determines if more tests, such as a lymph node biopsy, chest X-ray or blood tests, are needed. 

Treatments

Treatments

There is no one treatment for lymphadenopathy. Treatment is based on the cause. Once your child's doctor has diagnosed the underlying condition that is causing the lymph nodes to swell, he or she will prescribe treatment based on the underlying condition.

Key Points to Remember

Key Points to Remember

  • Lymph nodes help destroy infectious germs in the body, such as viruses and bacteria.
  • Swelling of the lymph nodes is a condition called lymphadenopathy.
  • Swollen lymph nodes can be a normal occurrence and may not show an underlying disorder or condition or require treatment.
  • If a lymph node becomes very swollen, it may indicate an underlying illness or disorder. 

Support Services & Resources

Support Services & Resources

Find more information on swollen lymph nodes at the trusted resources below.

We offer a broad range of supportive services to make life better for families who choose us for their children's care.

Learn More About Riley Support Services

MedlinePlus

This website from the U.S. National Library of Medicine shares images of the lymphatic system and a video about lymph nodes.

Locations

Locations

Locations

In addition to our primary hospital location at the Academic Health Center in Indianapolis, IN, we have convenient locations to better serve our communities throughout the state.

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Departments Treating This Condition

Departments Treating This Condition

  • Cancer & Blood Disorders
  • Infectious Diseases
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Designated as Best Children's Hospitals by U.S. News & World Report, Ranked in 10 Specialties in 2023-24

©2025 Riley Hospital for Children at
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Find adult services at iuhealth.org


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